Congratulations, Dr. Chaudhary!
News
Eui-Jin joined as an undergraduate intern.
Welcome, Eui-Jin!
Narendra’s work was published on Genome Research.
Here we developed an advanced CRISPR system to suppress background signals in genome imaging and used it to track the diffusion dynamics of small-repeat genomic loci.
Byeong-Kwon’s work was published on Nature Communications.
Here we revealed the dynamics of mitochondrial transcription initiation complexes in each step of the initiation stage and the transition to elongation.
We won an NRF “Post-Genome Project” grant for the study of cancer-specific modulation of chromatin structure and dynamics.
This grant is for the study of 3D and 4D structures of genome that are characteristic to breast cancer cell lines and patient samples, from live genome imaging approach, 0.3 billion won for 1.5 years.
Jooyoung joined as an undergraduate intern.
Welcome, Jooyoung!
Seung-Won’s work was published on Nucleic Acids Research.
In collaboration with Patel lab, this work revealed the role of C-terminal domain of the mitochondrial transcription initiation factor Mtf1 in controlling early transcription fidelity and the transition to elongation.
Our helicase study was published on Nucleic Acids Research.
In collaboration with Dr. Byungchan Ahn’s group, this work suggested a new mechanism of repetitive translocation of RecQ family helicases from single molecule measurements.
Seung-Won’s work on PCNA was published on Nature Communications.
In collaboration with Dr. Sukhyun Kang and Dr. Kyungjae Myung’s IBS center, this work revealed the loading and unloading mechanisms of PCNA by RFC and ATAD5-RLC from combined ensemble and single molecule approaches.
Hyunju’s work on DNA condensation was published on Nucleic Acids Research.
In collaboration with Dr. Jejoong Yoo and Dr. Aleksei Aksimentiev’s group, this work revealed a novel mechanism of sequence-dependent DNA condensation from single molecule measurements and molecular dynamics simulations.
We are participating in a newly launched SRC program of NRF, Cellular Responses to Metabolic Stress Research Center
The goal of this multi-disciplinary research center, led by Dr. Hyug Moo Kwon, is to reveal the mechanisms of cellular and inter-cellular responses to metabolic stress and the metabolic reprogramming.
Hajin’s work was published on Nature Communications.
This work reveals the evolution of RNA dynamics controlled by proteins during the hierarchical assembly of ribosomes.
Naren received Samsung Humatech Paper Award. Congratulations Naren!
Hayoon received best poster presentation award at The Korean Society for Molecular and Cellular Biology (KSMCB). Congratulations Hayoon!
Single molecule studies of the transcription initiation dynamics of yeast mitochondria
Nara received best poster presentation award in UNIST. Congratulations Nara!
Multiplexed CRISPR imaging for visualization of real-time chromatin dynamics
Hajin’s work was published on Nature Communications.
This study suggests a new, non-Watson-Crick mechanism for the sequence recognition between double-stranded DNAs, by their direct interaction through biogenic polyamine molecules.
Songyi Lee joined the lab. Welcome, Songyi!
Allyson Roberts from Johns Hopkins is visiting for 2 months thru SPIKE program. Let’s welcome Allyson!
Hajin’s work was published on BMC Research Notes.
This work describes a novel way of estimating kinetic parameters from single molecule lifetime data.
